Consider the facts:

Nitric Oxide is one of the most important molecules produced in your body to prevent cardiovascular disease
Pharmaceutical companies have been attempting to develop drugs around Nitric Oxide for years
Literally thousands of studies have been published on the importance of Nitric Oxide, in the most credible medical journals in the world

However, if you’ve even heard of Nitric Oxide, you probably associate it with the stuff you take during a workout. If you Google Nitric Oxide, the first several pages are all links related to someone trying to sell you a workout product. This is due primarily to the fact that a number of companies have exploited Nitric Oxide as a vasodilator that can enhance exercise performance and muscle gain by supplementing L-arginine. The vast majority of these products have no scientific basis for the claims they make, yet they are the top selling workout products on the market by far.

So despite over 100,000 publications in scientific and medical journals on sites like PubMed and Medline describing mechanisms of positive action and physiological effects of Nitric Oxide for serious medical conditions, a simple Google search for Nitric Oxide results in companies trying to sell you L-arginine for your workout! And while these supplements MAY be effective in some cases (primarily in young healthy athletes) this notion should be put in proper perspective.

First, L-arginine is not Nitric Oxide – it is an amino acid. L-arginine is metabolized by at least 8 different pathways and empirically only about 3% ends up in the Nitric Oxide pathway. Further, supplementing L-arginine to promote Nitric Oxide production in people with risk factors for heart disease such as smoking, obesity, high blood pressure, diabetes, high cholesterol, sedentary lifestyle and history of heart disease does not work. By definition these people have endothelial dysfunction, a clinical diagnosis which means that their endothelium (the cells that line every blood vessel in the body) cannot convert L-arginine into Nitric Oxide.

Hopefully you begin to see the problem with L-arginine-based supplements designed to enhance Nitric Oxide. The people that need Nitric Oxide the most cannot convert it, regardless of how much L-arginine they receive.

Our work at Neogenis has uncovered another way. Neo40 Daily’s proprietary blend of natural products with robust Nitric Oxide activity can overcome the body’s inability to convert L-arginine, and in fact utilizes a completely different production pathway. Thus Neo40 Daily can actually be effective as an exercise supplement for people over 40 or with risk factors, PLUS it actually helps promote cardiovascular health.

Before you buy any Nitric Oxide supplement, do your homework. Look past the marketing (and the bulging biceps) and understand the scientific basis for what they are selling. All Nitric Oxide supplements are NOT created equal.

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